产品货号：
GS4541
中文名称：
重组人4-1BBL
英文名称：
Recombinant Human 4-1BB Ligand
产品规格：
5μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 19.4kDa,a single non-glycosylated polypeptide chain containing 184 amino acids.
储存条件：冷冻（-20℃）
概述
4-1BBL is a member of the tumor necrosis factor(TNF)receptor family.This receptor contributes to the clonal expansion,survival,and development of T cells.In addition,4-1BBL expression is found on dendritic cells,follicular dendritic cells,natural killer cells,granulocytes and cells of blood vessel walls at sites of inflammation.CD137 has been shown to interact with TRAF2.The human 4-1BBL gene codes for a 254 amino acid type II transmembrane containing a 28 amino acid cytoplasmic domain,a 21 amino acid transmembrane domain,and a 205 amino acid extracellular domain(ECD).The human 4-1BBL ECD shares 32%and 35%a.a.identity with murine and rat ECD.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组人4-1BBL，4-1BBL, Human，Recombinant Human 4-1BB Ligand
储存条件：冷冻（-20℃）
概述
4-1BBL is a member of the tumor necrosis factor(TNF)receptor family.This receptor contributes to the clonal expansion,survival,and development of T cells.In addition,4-1BBL expression is found on dendritic cells,follicular dendritic cells,natural killer cells,granulocytes and cells of blood vessel walls at sites of inflammation.CD137 has been shown to interact with TRAF2.The human 4-1BBL gene codes for a 254 amino acid type II transmembrane containing a 28 amino acid cytoplasmic domain,a 21 amino acid transmembrane domain,and a 205 amino acid extracellular domain(ECD).The human 4-1BBL ECD shares 32%and 35%a.a.identity with murine and rat ECD.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞95%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The ED50 as determined by stimulation of IL-8 production using human PBMC is less than 10ng/ml,corresponding to a specific activity of>1.0×105 IU/mg. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution in PBS,pH 7.4. |
| 内毒素 | Less than 1 EU/μg of rHu4-1BBL as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 | REGPELSPDD PAGLLDLRQG MFAQLVAQNV LLIDGPLSWY SDPGLAGVSL TGGLSYKEDT KELVVAKAGV YYVFFQLELR RVVAGEGSGS VSLALHLQPL RSAAGAAALA LTVDLPPASS EARNSAFGFQ GRLLHLSAGQ RLGVHLHTEA RARHAWQLTQ GATVLGLFRV TPEIPAGLPS PRSE |
相关搜索：重组人4-1BBL，4-1BBL, Human，Recombinant Human 4-1BB Ligand